Thermo Fisher Scientific BTLA Monoclonal Antibody (1B7)
BTLA 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse 모노클론 항체(클론 1B7)입니다. Western blot과 ELISA에 적합하며, 인간 시료 반응성을 가집니다. PBS 버퍼에 보존되어 있으며 방부제 무첨가, -20°C에서 보관합니다.
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- H00151888-M02
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B7 |
| Immunogen | BTLA (NP_861445, 190–289 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DTAGREINLV DAHLKSEQTE ASTRQNSQVL LSETGIYDND PDLCFRMQEG SEVYSNPCLE ENKPGIVYAS LNHSVIGPNS RLARNVKEAP TEYASICVRS
Target Information
BTLA (B and T-lymphocyte attenuator) is a member of the co-inhibitory receptors of the CD28 superfamily.
It acts as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activation.
BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation.
It remains expressed on Th1 cells but not Th2 cells.
BTLA interacts with HVEM (herpesvirus entry mediator), a TNF receptor superfamily member, forming an important pathway for lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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