Thermo Fisher Scientific DEFB132 Polyclonal Antibody
인간, 마우스, 랫트 시료에서 DEFB132 단백질을 검출하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 실험에 적합하며, 친화 크로마토그래피로 정제됨. PBS/glycerol 완충액에 보관되며 -20°C에서 안정적 유지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DEFB132 (Accession Q7Z7B7), corresponding to amino acid residues A51–S95. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851748 |
Product Specific Information
Antibody detects endogenous levels of total DEFB132.
Target Information
Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi, and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated.
The family of beta-defensin proteins share a common defensin motif characterized by multiple cysteine residues and a highly conserved tertiary structure. In addition to their role in host immune defense, many beta-defensins are also involved in sperm maturation and capacitation.
Beta-defensin 32, also known as beta-defensin 132, is a 95-amino-acid secreted protein that likely contains a signal peptide sequence requiring proteolytic cleavage to become biologically active.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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