
Thermo Fisher Scientific HNRNPM Monoclonal Antibody (OTI6H7), TrueMAB
HNRNPM 단백질을 인식하는 Mouse monoclonal 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. Human 시료에 반응하며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되었고, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–261 of human HNRNPM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogeneous nuclear ribonucleoproteins (hnRNPs), play an important role in transcript-specific packaging and alternative splicing of pre-mRNAs.
The M1–M4 proteins form a cluster of four abundant hnRNPs that bind pre-mRNA in vivo and poly(G)/poly(U) RNA homopolymers in vitro.
They belong to the ribonucleoprotein consensus sequence family and possess an MR repeat motif similar to that in the 64 kDa subunit of cleavage stimulation factor involved in pre-mRNA 3'-end maturation.
Proteins immunologically related to M are found in diverse eukaryotes from human to yeast.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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