Thermo Fisher Scientific Phospho-Raptor (Ser863) Polyclonal Antibody
Raptor 단백질의 Ser863 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot에 최적화되어 있으며, 사람, 생쥐, 랫트 시료에 반응. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPTOR (Accession Q8N122), corresponding to amino acid residues around phosphorylated Ser863. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817601 |
Product Specific Information
Antibody detects endogenous levels of Raptor only when phosphorylated at Ser863.
Target Information
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of RAPTOR to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro and enhances the mTOR kinase activity toward p70alpha. It also serves as an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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