Thermo Fisher Scientific CD62E/CD62P Monoclonal Antibody (1.2B6), PE

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

3 µL/10^6 cells

-

Product Specifications

Species Reactivity

Human, Pig

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1.2B6

Immunogen

TNF stimulated human endothelial cells if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD62E/CD62P,uniProtId:P16109-1,ncbiNodeId:9606,antigenRange:1-830,antigenLength:830,antigenImageFileName:MA5-28649_CD62ECD62P_P16109-1_House_mouse.svg,antigenImageFileNamePDP:MA5-28649_CD62ECD62P_P16109-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:CD62E/CD62P,uniProtId:P16581-1,ncbiNodeId:9606,antigenRange:1-610,antigenLength:610,antigenImageFileName:MA5-28649_CD62ECD62P_P16581-1_House_mouse.svg,antigenImageFileNamePDP:MA5-28649_CD62ECD62P_P16581-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

PE PE PE

View additional formats

• APC
• Biotin
• FITC
• PE-Cyanine5
• Request custom conjugation

Excitation/Emission Max

565/576 nm View spectra

Form

Liquid

Concentration

0.1 mg/mL

Purification

purified

Storage buffer

PBS, pH 7.5, with proprietary stabilizer

Contains

<0.1% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2745608

Target Information

CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.