Thermo Fisher Scientific RUNX1 Monoclonal Antibody (3A8)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1.2 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

3A8

Immunogen

RUNX1 (NP_001001890.1, 210 a.a. approximately 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RUNX1,uniProtId:Q01196-1,ncbiNodeId:9606,antigenRange:210-310,antigenLength:453,antigenImageFileName:H00000861-M01_RUNX1_Q01196-1_House_mouse.svg,antigenImageFileNamePDP:H00000861-M01_RUNX1_Q01196-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: RVSPHHPAPT PNPRASLNHS TAFNPQPQSQ MQDTRQIQPS PPWSYDQSYQ YLGSIASPSV HPATPISPGR ASGMTTLSAE LSSRLSTAPD LTAFSDPRQF P

Target Information

RUNX1 belongs to the mammalian RUNX family of DNA binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX1 is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac and placenta. RUNX1 is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow and peripheral blood.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.