Thermo Fisher Scientific IL17RD Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human IL17RD. Recombinant protein control fragment (Product #RP-96358). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL17RD,uniProtId:Q8NFM7-1,ncbiNodeId:9606,antigenRange:194-283,antigenLength:739,antigenImageFileName:PA5-111112_IL17RD_Q8NFM7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-111112_IL17RD_Q8NFM7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856522

Product Specific Information

Immunogen sequence: LACKPFWKPR NLNISQHGSD MQVSFDHAPH NFGFRFFYLH YKLKHEGPFK RKTCKQEQTT ETTSCLLQNV SPGDYIIELV DDTNTTRKVM

Target Information

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.