Thermo Fisher Scientific IL17RD Polyclonal Antibody
Human IL17RD를 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. FGF 관련 신호전달 억제 연구에 적합.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human IL17RD. Recombinant protein control fragment (Product # RP-96358) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856522 |
Product Specific Information
Immunogen sequence:
LACKPFWKPR NLNISQHGSD MQVSFDHAPH NFGFRFFYLH YKLKHEGPFK RKTCKQEQTT ETTSCLLQNV SPGDYIIELV DDTNTTRKVM
Target Information
Feedback inhibitor of fibroblast growth factor (FGF) mediated Ras-MAPK signaling and ERK activation.
May inhibit FGF-induced FGFR1 tyrosine phosphorylation.
Regulates nuclear ERK signaling by blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation.
Mediates JNK activation and may be involved in apoptosis.
Might play a role in early fate specification of GnRH-secreting neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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