Thermo Fisher Scientific TM2D1 Polyclonal Antibody
TM2D1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·생쥐·랫드 시료에 반응합니다. Western blot에 적합하며 Alzheimer’s disease 관련 연구에 유용합니다. 액상 형태로 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human TM2D1 (aa 53–73) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2692056 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Proteolytic cleavage of the Amyloid protein precursor (APP) generates β-Amyloid and Amyloid A4 proteins, found in human platelets. Amyloid deposition is associated with type II diabetes, Down syndrome, and neurological disorders including Alzheimer’s disease. BBP (Beta-amyloid-binding protein), also known as TM2D1, is a 207 amino acid multi-pass membrane protein with a G protein-coupling module that interacts with the β-amyloid peptide of APP. In cell culture, BBP expression induces caspase-dependent vulnerability to β-amyloid peptide toxicity, suggesting a role in Alzheimer’s disease pathophysiology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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