Thermo Fisher Scientific GPR17, G Protein-coupled Receptor 17 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide presents the carboxyl - terminal tail of human GPR17. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR17,uniProtId:Q13304-1,ncbiNodeId:9606,antigenRange:367,antigenLength:367,antigenImageFileName:7TM0088N_GPR17_Q13304-1_Rabbit.svg,antigenImageFileNamePDP:7TM0088N_GPR17_Q13304-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

Dulbecco`s PBS, pH 7.4

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.