Thermo Fisher Scientific EIF3L Polyclonal Antibody
EIF3L 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 Immunoprecipitation에 적합. 액상 형태로 제공되며 4°C에서 보관. 인간 EIF3L의 514-564번 잔기 영역을 면역원으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 514–564 of human Eukaryotic Translation Initiation Factor 3 Subunit L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Chicken, Bovine, and Chimpanzee
Target Information
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S pre-initiation complex (43S PIC). It stimulates mRNA recruitment and scanning for AUG recognition, and is essential for ribosomal recycling and prevention of premature subunit joining. The complex selectively regulates translation of mRNAs involved in cell proliferation, differentiation, and apoptosis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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