Thermo Fisher Scientific Sulfate Latex Beads, 8% w/v, 0.5 μm

Invitrogen™ Sulfate Latex Beads, 8% w/v, 0.5 μm

Microspheres (also called latex beads or latex particles) are spherical particles in the colloidal size range formed from an amorphous polymer such as polystyrene.
Because of the way that the polystyrene chains arrange themselves in the bead, the surface is highly hydrophobic, making these ideal materials for the adsorption of proteins.

These sulfate latex microspheres are stabilized by sulfate charges. In some cases, hydroxyl and carboxyl groups are also present in small amounts bound to the polymer chains.
The pKa of the sulfate group is <2, and consequently, the particles are stable in acidic media. Suspensions remain stable up to nearly 0.30 M univalent electrolyte concentrations, allowing use in physiological ionic strength media.
However, they are hydrophobic particles and may aggregate in the presence of divalent or trivalent cations unless stabilized by a hydrophilic coating.

Sulfate latex beads are suitable for calibration of particle size analysis equipment and for diagnostic test systems that rely on physical adsorption of antigens or antibodies.

Microspheres Are Available in Many Sizes and Surface Functionalities

• 25 sizes to choose from (0.02 μm to 16 μm)
• 20 different surface chemistries for ready conjugation
• Surfactant-free, ultraclean formulation
• Available in quantities from milliliters to 500 liters

Key Applications

• Instrument calibration (flow cytometry, microscopy, HTS, HCS)
• Flow testing (microfluidics, blood flow, water flow, air flow)
• Cell biology tracers (cell differentiation and tracing)
• Immunoassays (agglutination tests, ELISA, particle capture, contrast reagents)

Additional Information

Read a technical overview of microspheres and learn about high activity beads, super active beads, specialty beads, and bead-coupling protocols on the IDC Surfactant-free Latex Beads page.

Custom Microsphere Service

If you don’t find the microsphere you need in our stocked list, we offer custom microsphere manufacturing.
Our custom conjugation service is efficient, confidential, and ISO 13485:2000 certified.

For Research Use Only. Not intended for animal or human therapeutic or diagnostic use.

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