
Thermo Fisher Scientific CD44 Monoclonal Antibody (OX-50), PE
Flow Cytometry용 CD44 단클론 항체(OX-50), PE 형광표지. Rat 시료 반응성, Mouse IgG1 아이소타입. Protein A 정제, PBS 기반 완충액에 5% sucrose, 1% BSA, 0.09% sodium azide 포함. 4°C 암소 보관, 동결 금지. 연구용 전용.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat
View 6 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-50 |
| Immunogen | Rat T cell blasts |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Protein A |
| Storage Buffer | PBS with 5% sucrose, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538386 |
Additional Formats
Product Specific Information
- Reconstitute with 1 mL of distilled water.
- After reconstitution, store product undiluted at 4°C in the dark.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Target Information
CD44 is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leukocytes, white matter of the brain, and some epithelial cells of the intestine and breast.
It acts as a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration.
CD44 participates in lymphocyte activation, recirculation, and homing, and may be upregulated in certain carcinomas related to metastatic potential.
It is expressed by hematopoietic and non-hematopoietic cells, epithelial tissues, and filopodia in cultured keratinocytes.
Alternative splicing generates multiple isoforms with distinct functions.
Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus.
CD44 may also be related to tumor metastasis formation.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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