Thermo Fisher Scientific SFTPD Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-220 of human Surfactant protein D/SP-D (NP_0030104) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SFTPD,uniProtId:P35247-1,ncbiNodeId:9606,antigenRange:50-220,antigenLength:375,antigenImageFileName:PA5-110362_SFTPD_P35247-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110362_SFTPD_P35247-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.48 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855773

Product Specific Information

Immunogen sequence: RDGRDGREGP RGEKGDPGLP GAAGQAGMPG QAGPVGPKGD NGSVGEPGPK GDTGPSGPPG PPGVPGPAGR EGPLGKQGNI GPQGKPGPKG EAGPKGEVGA PGMQGSAGAR GLAGPKGERG VPGERGVPGN TGAAGSAGAM GPQGSPGARG PPGLKGDKGI PGDKGAKGES G

Target Information

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.