Thermo Fisher Scientific TOP2A Recombinant Rabbit Monoclonal Antibody (ARC0994)
Recombinant rabbit monoclonal antibody targeting TOP2A for detection in human and mouse samples. Validated for Western blot and ELISA. High specificity and reproducibility. Supplied as liquid form with 0.25 mg/mL concentration. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0994 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1432–1531 of human DNA topoisomerase II alpha (TOP2A) (P11388) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849404 |
Product Specific Information
Immunogen sequence:
AKKRAAPKGT KRDPALNSGV SQKPDPAKTK NRRKRKPSTS DDSDSNFEKI VSKAVTSKKS KGESDDFHMD FDSAVAPRAK SVRAKKPIKY LEESDEDDLF
Target Information
Topo II alpha plays important roles in DNA synthesis and transcription as well as chromosomal segregation during mitosis. It is a sensitive and specific marker of late S-, G2, and M-phases in transformed and developmentally regulated normal cells. Topo II alpha is also implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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