Thermo Fisher Scientific CTSK Monoclonal Antibody (2F1)
인간 Cathepsin K 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot, IHC, ELISA 등에 사용 가능. 액상 형태로 제공되며 PBS(pH 7.4)에 보존제 없이 저장. 뼈 재형성과 종양 침습 연구에 적합한 연구용 시약.
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Thermo Fisher Scientific CTSK Monoclonal Antibody (2F1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 3 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F1 |
| Immunogen | CTSK (AAH16058, 220–329 a.a.) partial recombinant protein with GST tag (MW 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KCRGYREIPE GNEKALKRAV ARVGPVSVAI DASLTSFQFY SKGVYYDESC NSDNLNHAVL AVGYGIQKGN KHWIIKNSWG ENWGNKGYIL MARNKNNACG IANLASFPKM
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. It belongs to the peptidase C1 protein family and is predominantly expressed in osteoclasts. It is also expressed in a significant fraction of human breast cancers, potentially contributing to tumor invasiveness. Mutations in this gene cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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