Thermo Fisher Scientific Caspase 4 Polyclonal Antibody
Caspase 4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 인간 및 설치류 등 여러 종에 반응합니다. 고순도 Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공합니다.
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Thermo Fisher Scientific Caspase 4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Caspase 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903380 |
Product Specific Information
Antibody detects endogenous levels of total Caspase 11.
Target Information
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and large and small protease subunits. Activation requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of large and small subunits. This caspase can cleave and activate its own precursor protein as well as the caspase 1 precursor. Overexpression of this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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