
Thermo Fisher Scientific ATOH1 Monoclonal Antibody (4H2)
ATOH1 단백질을 인식하는 마우스 단클론 항체(4H2)로, WB, ICC/IF, ELISA에 최적화됨. 인간 단백질에 반응하며 비결합형 액상 형태로 제공. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능.
- 카탈로그번호
- H00000474-M09
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H2 |
| Immunogen | ATOH1 (NP_005163.1, 266–354 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
PTPPGSCRTR FSAPASAGGY SVQLDALHFS TFEDSALTAM MAQKNLSPSL PGSILQPVQE ENSKTSPRSH RSDGEFSPHS HYSDSDEAS
Target Information
The Drosophila atonal gene encodes a protein with basic helix-loop-helix (bHLH) domains essential for nervous system development. Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid HLH transcription factor homologous to Drosophila atonal. In mice, MATH-1 expression begins around embryonic day 9.5, localizing to cranial ganglia and dorsal CNS regions. By day 18, expression becomes restricted to the external granular layer of the cerebellum and is undetectable in adults. MATH-1 is suggested to regulate neural cell differentiation by activating E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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