Thermo Fisher Scientific CSPG5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CSPG5 (Neuroglycan C). Validated for ICC/IF applications. Supplied as liquid, unconjugated form with antigen affinity purification. Suitable for neuroscience and developmental biology research.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CSPG5. Recombinant protein control fragment (Product #RP-106237) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662272 |
Product Specific Information
Immunogen sequence:
SLSTIAEGSHP NVRKLCNTPR TSSPHARALA HYDNVICQDD PSAPHKIQEV LKSCLKEEES FNIQNSMSPK LEGGKGDQAD LDVNCL
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 89%
Target Information
Neuroglycan C (CSPG5) is a transmembrane chondroitin sulfate proteoglycan expressed exclusively in the central nervous system. NGC gene expression is developmentally regulated and can be altered by psychostimulant addiction or nerve injury.
Its core protein features a unique multidomain structure distinct from other proteoglycans and undergoes post-translational modifications such as phosphorylation and glycosylation.
Neuroglycan C acts as a part-time proteoglycan, transitioning between proteoglycan and non-proteoglycan forms during cerebellum and retina development.
Evidence suggests its involvement in neuronal circuit formation within the CNS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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