
Thermo Fisher Scientific AMACR/p504S Recombinant Mouse Monoclonal Antibody (rAMACR, 4674)
인간 AMACR 단백질을 인식하는 재조합 마우스 단클론 항체. 포르말린 고정 파라핀 절편 조직의 IHC(P) 분석에 적합. Protein A/G로 정제된 액상 형태로 제공되며, 보존제 무첨가 PBS(pH 7.4) 용액에 1 mg/mL 농도로 공급. 연구용 전용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rAMACR, 4674 |
| Immunogen | Recombinant full-length human AMACR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme in the β-oxidation of branched-chain fatty acids.
High expression of P504S protein is observed in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining of paraffin-embedded sections.
Expression is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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