Thermo Fisher Scientific LDHA Polyclonal Antibody
LDHA 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합합니다. 인간 및 여러 종에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용 전용 제품입니다.
- 카탈로그번호
- PA526531
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LDHA Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Fruit fly, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 154–182 of human LDHA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.34 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2544031 |
Product Specific Information
This antibody is predicted to react with bovine, porcine, non-human primate, and rat based on sequence homology.
Target Information
Lactate dehydrogenase (LDH) is an enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD⁺. In mammals, the enzyme is encoded by three genes: LDHA (M form), LDHB (H form), and LDHC (X form).
The three human LDHs share 84–89% sequence similarity and 69–75% amino acid identity. There are five LDH isoenzymes based on the ratio of M and H chains in the tetrameric structure.
LDHA is hypoxia-inducible and regulated by the transcriptional activity of hypoxia-inducible factor 1α (HIF1α). LDHB is also upregulated in many cancers. Mutations in the LDHA gene can cause Glycogen storage disease 11 (GSD11).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.