Thermo Fisher Scientific ASCC1 Monoclonal Antibody (OTI6G5), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The ASCC1 gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex, a transcriptional coactivator involved in gene transactivation by multiple transcription factors such as AP-1, NF-κB, and SRF.
The encoded protein includes an N-terminal KH-type RNA-binding motif required for AP-1 transactivation by the ASC-1 complex.
Mutations in ASCC1 are associated with Barrett esophagus and esophageal adenocarcinoma.
Multiple alternatively spliced transcript variants encoding different isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.