Thermo Fisher Scientific PCDHA12 Polyclonal Antibody
Human PCDHA12 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PCDHA12. Recombinant protein control fragment (Product #RP-103949). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790446 |
Product Specific Information
Immunogen sequence:
LNGEISYGIK MILPVSEKCM FSINPDTGEI RIYGELDFEE NNAYEIQVNA IDKGIPSMAG HSMVLVEV
Target Information
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.
The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences.
The tandem array of 15 N-terminal exons (variable exons) are followed by downstream C-terminal exons (constant exons), which are shared by all genes in the cluster.
These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that likely play a critical role in establishing and maintaining specific cell-cell connections in the brain.
Alternative splicing has been observed, and additional variants have been suggested but not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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