Thermo Fisher Scientific RAD51 Polyclonal Antibody
RAD51 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC(Paraffin) 실험에 적합. 고순도(>95%) 항원 친화 크로마토그래피로 정제됨. 인간 및 생쥐 반응성. DNA 복구 연구 및 RAD51 관련 기전 연구용.
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Thermo Fisher Scientific RAD51 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 280–330 of Human Rad51 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803411 |
Product Specific Information
Purity is greater than 95% by SDS-PAGE.
Target Information
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recombination. It binds to single- and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments essential for homology search and strand exchange. Mutations in the RAD51 gene can result in breast cancer, mirror movements 2, and Fanconi anemia.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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