Thermo Fisher Scientific Human SAPAP3 Synthetic Peptide
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PEP0582 | - | Thermo Fisher Scientific PEP0582 Human SAPAP3 Synthetic Peptide 50 ug pk | 재고문의 | pk | 196,000원 | - | 215,600원 |
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Applications
Tested Dilution
Publications
Control (Ctrl)
Assay-dependent
Blocking Assay (BLOCK)
Assay-dependent
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human SAPAP3.
PEP-0582 can be used as a blocking peptide with polyclonal antibody PA5-20465.
Target Information
SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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