Thermo Fisher Scientific CD45RC Monoclonal Antibody (3a56), Alexa Fluor 647

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1:100

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3a56

Conjugate

Alexa Fluor™ 647 Alexa Fluor™ 647 Alexa Fluor™ 647

View additional formats

• Unconjugated
• PE
• Request custom conjugation

Excitation/Emission Max

650/671 nm View spectra

Form

Liquid

Concentration

0.05 mg/mL

Storage conditions

4°C or -20°C if preferred, store in dark

Shipping conditions

Wet ice

Target Information

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.