Thermo Fisher Scientific FGF4 Polyclonal Antibody
FGF4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
- Publications: View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGF4. Recombinant protein control fragment (Product #RP-89876) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641610 |
Product Specific Information
Immunogen sequence:
VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFL
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 91%
Target Information
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family with broad mitogenic and cell survival activities. It plays key roles in stem cell growth and survival during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 is a potent angiogenic factor expressed in highly vascularized tumors and adult mouse testis, intestine, and brain. Mouse homolog studies suggest roles in bone morphogenesis and limb development via the sonic hedgehog (SHH) signaling pathway. Additionally, FGF4 regulates neural progenitor proliferation and neuronal differentiation. Recent findings indicate a growth-promoting role in human embryonic stem cells and a feedback inhibition mechanism via a novel splice isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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