Thermo Scientific™

Tango™ GPR39-bla U2OS Cells

Tango™ GPR39-bla U2OS cells contain the orphan human G-protein Coupled Receptor 39 (GPR39) linked to a TEV protease site and자세히 알아보기

Tango™ GPR39-bla U2OS cells contain the orphan human G-protein Coupled Receptor 39 (GPR39) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR39-bla U2OS cells have been functionally validated for a receptor specific response to FBS. In addition, Tango™ GPR39-bla U2OS cells have been tested for assay performance under variable conditions.

사양

등록 번호NM_001508.1

어세이 입력Cell-based beta-arrestin recruitment

셀 상태Dividing Cells

세포질 후미Native Tail

검출 방법Fluorescence

용도(애플리케이션)FRET

유전자 기호GPR39

인간 단백질 분류G-Protein Coupled Receptor (GPCR)

개체군 상태Pool of Stable Cells

제품라인Tango™

수량8 x 106 Cells

판독End Point

타겟 입력GPR39

세포주U2OS

System TypeTango™

Druggable TargetGPCR

Unit SizeEach