Thermo Fisher Scientific HLA-G Monoclonal Antibody (1E7)
Thermo Fisher Scientific의 HLA-G 단일클론 항체(1E7)는 인간 HLA-G 단백질을 인식하는 Mouse IgG1 항체로, Western blot 및 ELISA에 적합합니다. PBS(pH 7.4) 용액 형태로 제공되며, 보존제 없이 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E7 |
| Immunogen | A synthetic peptide corresponding to human HLA-G (amino acids 166–188; UniProt ID: P17693-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
The sequence of this protein is as follows:
ISKRKCEAAN VAEQRRAYLE GTC
Target Information
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal-derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.
Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains (which bind the peptide), exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
HLA and MHC antibodies play a significant role in immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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