Thermo Fisher Scientific Complement C2 Polyclonal Antibody
Human, Mouse, Rat 반응성의 Rabbit Polyclonal Anti-Complement C2 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합함. KLH 결합 합성 펩타이드(Complement C2a fragment, aa 401-500)를 면역원으로 사용. 고순도 Protein A 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific Complement C2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Complement C2a fragment, amino acids 401–500 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Complement component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a combines with complement factor 4b to form the C3 or C5 convertase. Deficiency of C2 is associated with certain autoimmune diseases, and SNPs in this gene have been linked to altered susceptibility to age-related macular degeneration. The gene is localized within the class III region of the MHC on chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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