Thermo Fisher Scientific NO66 Polyclonal Antibody
Thermo Fisher Scientific의 NO66 Polyclonal Antibody는 인간 NO66 단백질을 인식하는 토끼 IgG 기반 항체입니다. ICC/IF 실험에 적합하며, 0.25–2 µg/mL 농도로 사용됩니다. 액상 형태로 제공되며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NO66. Recombinant protein control fragment (Product #RP-105694) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664782 |
Product Specific Information
Immunogen sequence:
RVVETSALLCT AQHLAAVQSS GAPATASGPQ VDNTGGEPAW DSPLRRVLAE LNRIPSSRRR AARLFEWLIA PMPPDHFYRR LWEREAVLVR RQDHTYYQGL FSTADLDSML RNEEVQFGQH LDAARYINGR R
Highest antigen sequence identity to the following orthologs:
- Mouse: 61%
- Rat: 66%
Target Information
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates Lys-4 (H3K4me) and Lys-36 (H3K36me) of histone H3, playing a central role in histone code regulation. Preferentially demethylates trimethylated H3 Lys-4 (H3K4me3) and monomethylated H3 Lys-4 (H3K4me1), with weaker activity for dimethylated H3 Lys-36 (H3K36me2). Catalyzes hydroxylation of 60S ribosomal protein L8 on His-216. Acts as a regulator of osteoblast differentiation via interaction with SP7/OSX, inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and heterochromatin remodeling. Participates in MYC-induced transcriptional activation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-64895_NO66_Q9H6W3-1_Rabbit.svg
- PA5-64895_NO66_Q9H6W3-1_Rabbit_PDP.jpeg
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