Thermo Fisher Scientific MRPS35 Polyclonal Antibody
MRPS35 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 및 글리세롤 버퍼에 보관하며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPS35. Recombinant protein control fragment (Product #RP-97649). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644200 |
Product Specific Information
Immunogen sequence:
DMEEYIWENS SSERNILETL LQMKAAEKNM EINKEELLGT KEIEEYKKSV VSLKNEEENE NSISQYKESV K
Highest antigen sequence identity to the following orthologs:
- Mouse: 63%
- Rat: 65%
Target Information
Mammalian mitochondrial ribosomes (mitoribosomes) are responsible for protein synthesis within the mitochondrion. The mitoribosomes are composed of a 4:1 ratio of protein to RNA, forming two subunits — the 28S and 39S. Across species, mitoribosomal proteins vary greatly in sequence, limiting recognition by homology.
MRP-S35 (mitochondrial ribosomal protein S35), also known as MDS023, MRPS28, or HDCMD11P, is a 323 amino acid protein localized in the mitochondrion as part of the 28S ribosomal subunit. It functions with other MRPs to mediate mitochondrial protein synthesis. Two alternatively spliced isoforms exist, and the gene is located on human chromosome 10, which contains over 1,200 genes and represents approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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