Thermo Fisher Scientific FNDC4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FNDC4. Recombinant protein control fragment (Product #RP-103724). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FNDC4,uniProtId:Q9H6D8-1,ncbiNodeId:9606,antigenRange:47-100,antigenLength:234,antigenImageFileName:PA5-64124_FNDC4_Q9H6D8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64124_FNDC4_Q9H6D8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641700

Product Specific Information

Immunogen sequence: PPSPVNVTVT HLRANSATVS WDVPEGNIVI GYSISQQRQN GPGQRVIREV NTTT

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 63%.

Target Information

Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.