Thermo Fisher Scientific CWC22 Polyclonal Antibody
CWC22 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow Cytometry 등 다양한 응용에 적합. 고순도 Protein A 및 항원 친화 크로마토그래피로 정제. 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 16–45 amino acids from the N-terminal region of human CWC22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541776 |
Target Information
Required for pre-mRNA splicing as a component of the spliceosome (PubMed:12226669, 11991638, 22961380, 28502770, 28076346, 29360106, 29301961).
Promotes exon-junction complex (EJC) assembly (PubMed:22959432, 22961380).
Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs.
Through its role in EJC assembly, required for nonsense-mediated mRNA decay. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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