Thermo Fisher Scientific Phospho-PTPN7 (Ser93) Polyclonal Antibody
Phospho-PTPN7 (Ser93) 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응. WB, IHC, ICC, ELISA 등 다양한 응용 가능. KLH 결합 합성 인산화 펩타이드 면역원 사용. Protein A 정제, 고농도(1 mg/mL) 액상 형태로 안정적 보관.
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Thermo Fisher Scientific Phospho-PTPN7 (Ser93) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human PTPN7 around the phosphorylation site of Ser93 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells. Its noncatalytic N-terminus interacts with MAP kinases and suppresses their activity, playing a role in T-cell antigen receptor signaling through dephosphorylation of MAP kinase pathway molecules. Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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