Thermo Fisher Scientific JIP2 Polyclonal Antibody
Rabbit polyclonal antibody against human JIP2 protein. Validated for IHC (Paraffin) with dilution 1:20–1:50. Affinity purified and supplied in PBS with glycerol. Suitable for research on MAPK signaling pathways in brain and pancreatic cells.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human JIP2. Recombinant protein control fragment (Product # RP-94964) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642847 |
Product Specific Information
Immunogen sequence:
FSLSTFHSLS PPGCRPPQDI SLEEFDDEDL SEITDDCGLG LSYDSDHCEK DSLSLGRSEQ PHPICSFQDD FQEFEM
Antigen sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein involved in the c-Jun N-terminal kinase (JNK) signaling pathway. It is expressed in brain and pancreatic cells and interacts with MAPK8/JNK1 and MAP2K7/MKK7 kinases, functioning as a regulator of signal transduction in these tissues. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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