
Thermo Fisher Scientific CD138 Monoclonal Antibody (1D4), PE-Cyanine5.5
PE-Cyanine5.5 형광 접합체로 멀티컬러 분석에 적합한 CD138 단클론 항체. Flow Cytometry용으로 검증됨. 인간 CD138 인식, 마우스 IgG1 아이소타입. 4°C 암소 보관 및 Wet ice 배송.
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Applications
- Flow Cytometry (Flow): Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D4 |
| Immunogen | Human CD138 |
| Conjugate | PE-Cyanine5.5 |
| Excitation / Emission Max | 564 / 692 nm |
| Form | Liquid |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_10373394 |
Product Specific Information
The R-phycoerythrin (PE)-Cy5.5 tandem conjugate permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source—the 488 nm line of the argon-ion laser.
Target Information
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes.
CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells, and endothelial cells.
Up-regulation and down-regulation of CD138 on the cell surface often correlate with the gain of cancerous characteristics. Serum levels of the shed soluble sCD138 are used as a prognostic factor of cancerogenesis.
Analyte Specific Reagent
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