Thermo Fisher Scientific VNN1 Monoclonal Antibody (D1)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Pig

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

D1

Immunogen

Recombinant Human VNN1 protein, Leu36-Leu223 (Accession #O95497) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VNN1,uniProtId:O95497-1,ncbiNodeId:9606,antigenRange:36-223,antigenLength:513,antigenImageFileName:MA5-51153_VNN1_O95497-1_House_mouse.svg,antigenImageFileNamePDP:MA5-51153_VNN1_O95497-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3093354

Target Information

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.