Thermo Fisher Scientific Phospho-PDGFRB (Tyr751) Polyclonal Antibody
PDGFRB (Tyr751) 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot과 유세포분석에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 보존제 무첨가 액상 형태로 제공. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr751 of human PDGF receptor β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 14 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986102 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PDGFRB is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for mesenchymal-origin cells. The receptor may form homodimers or heterodimers with PDGF receptor alpha, depending on the bound growth factor. The PDGFRB gene is located on chromosome 5, near genes for GM-CSF and M-CSF receptor, and may be involved in the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) with ETV6 results in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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