Thermo Fisher Scientific DNAJB4 Polyclonal Antibody
Human DNAJB4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제된 액상 형태로 장기 보관 시 -20°C에서 안정적.
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Thermo Fisher Scientific DNAJB4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNAJB4. Recombinant protein control fragment (Product #RP-94390). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640682 |
Product Specific Information
Immunogen sequence:
SNPFEIFFGR RMGGGRDSEE MEIDGDPFSA FGFSMNGYPR DRNSVGPSRL KQDPPVIH
Highest antigen sequence identity to orthologs:
- Mouse: 98%
- Rat: 97%
Target Information
DnaJ heat shock induced proteins originate from Escherichia coli and are regulated by the htpR regulatory protein. These proteins play a critical role in the HSP70 chaperone system by interacting with HSP70 to stimulate ATP hydrolysis. They contain cysteine-rich zinc finger regions forming a peptide-binding domain responsible for chaperone function. DnaJ proteins mediate proteolysis and regulate protein degradation, exocytosis, and endocytosis.
DnaJB4 (DnaJ homolog subfamily B member 4), also known as HLJ1, is expressed in skeletal muscle, heart, and pancreas, with lower expression in brain, placenta, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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