Thermo Fisher Scientific SPIN90 Polyclonal Antibody
Rabbit polyclonal antibody targeting SPIN90 (NCKIPSD) for IHC applications. Recognizes residues 600–650 of human SH3 protein interacting with Nck. Supplied as liquid, unconjugated form at 0.25 mg/mL. Recommended storage at 4°C with 1-year shelf life.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 600 and 650 of Human SH3 protein interacting with Nck (90 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with:
Guinea pig_10141, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Chinese hamster, and White-tufted-ear marmoset
Target Information
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation.
The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene.
Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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