Thermo Fisher Scientific CD79a Monoclonal Antibody (HM47/A9)
CD79a 단백질을 인식하는 HM47/A9 클론의 단일클론 항체로, WB, IHC(P), ICC/IF에 적합합니다. 다양한 종(인간, 마우스, 랫 등)에 반응하며, 액상형으로 4°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:25–1:50 | – |
| Immunohistochemistry (IHC) | – | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 | – |
| Immunocytochemistry (ICC/IF) | 1:100 | – |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HM47/A9 |
| Immunogen | Synthetic peptide GTYQDVGSLNIADVQ (human CD79a, aa 208–222) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 400 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981393 |
Product Specific Information
- MA5-13212 targets CD79a in IF, IHC (P), and WB applications.
- Reactivity observed with Bovine, Equine, Guinea Pig, Human, Mouse, Non-human primate, Porcine, Rabbit, Chicken, and Rat samples.
- The immunogen is a synthetic peptide (GTYQDVGSLNIADVQ) derived from human CD79a.
- Not functional in IHC (P) in its B format.
Target Information
CD79a is a disulphide-linked heterodimer including the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for B-cell receptor expression and signaling.
CD79a expression begins at the pre-B cell stage and continues to the plasma cell stage, where it becomes intracellular. It is found in most precursor B-cell acute leukemias, B-cell lines, lymphomas, and some myelomas, but absent in myeloid or T-cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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