Thermo Fisher Scientific FLT3 Monoclonal Antibody (OTI7D6), TrueMAB
FLT3 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI7D6). Western blot에 최적화되어 있으며, Human 시료에 반응. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
- 카탈로그번호
- TA808157
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 169–444 of human FLT3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FLT3 is a tyrosine protein kinase and a member of the growth factor receptor tyrosine kinase family. Activation occurs upon binding of the FLT3 ligand to the extracellular domain, inducing receptor homodimerization and autophosphorylation. The activated receptor phosphorylates multiple downstream effectors involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Constitutive activation mutations are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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