Thermo Fisher Scientific AUH Polyclonal Antibody
Thermo Fisher Scientific의 AUH Polyclonal Antibody는 인간 AUH 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot, IHC, IP 등 다양한 응용에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5112239
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific AUH Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 0.5–2 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human AUH fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866975 |
Target Information
Methylglutaconyl-CoA hydratase (AUH) is a mitochondrial protein that binds to AU-rich elements (AREs) commonly found in the 3′ UTR of rapidly decaying mRNAs such as c-fos, c-myc, and granulocyte/macrophage colony-stimulating factor. These ARE elements promote RNA degradation and deadenylation.
AUH shares homology with enoyl-CoA hydratase, an enzyme involved in fatty acid metabolism, and exhibits intrinsic hydratase activity. It functions as a bifunctional protein with both RNA-binding and metabolic roles. The mouse homolog, sharing 92% identity with the human protein, localizes to mitochondria, suggesting AUH may act as a mitochondrial AU-binding protein. Human AUH is expressed as a single 1.8 kb mRNA, producing a 40 kDa precursor that is processed into a 32 kDa mature form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.