Thermo Fisher Scientific Pan B Cells Monoclonal Antibody (CVS36), FITC

Applications

Flow Cytometry (Flow)

• Tested Dilution: Assay-dependent

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Additional Formats

• Unconjugated (MA5-28501)
• PE (MA5-28500)
• Request custom conjugation

Product Specific Information

This antibody recognizes equine Ig light chains. Characterization studies demonstrated that clone CVS36 bound 100% of CD5-ve peripheral blood lymphocytes and recognized all equine B-cells.

Target Information

Pan B Cells antibody specific anti-equine reagents have yet to be fully characterized for the typically recognized B-cell markers such as CD19, CD20, CD21, CD22, and CD79. While testing has demonstrated the cross-reactivity of some monoclonal B-cell markers raised against other species with equine B cells (e.g., Mouse anti-Human CD79a antibody, clone HM57), Pan B Cells antibody is directed against equine Ig light chains. Characterization studies demonstrated that clone CVS36 bound 100% of CD5-ve peripheral blood lymphocytes and recognized all equine B-cells (Lunn et al. 1998). As the antigen recognized by clone CVS36 appears to be present on the surface of all equine B-cells, it can be used as a pan B-cell marker for domestic horses.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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