Thermo Fisher Scientific DCT Polyclonal Antibody
DCT 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC(Paraffin), Flow Cytometry에 사용 가능. Protein A 및 항원 친화 크로마토그래피로 정제. 인체 시료 반응성. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 62–89 of the N-terminal region of human DCT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718425 |
Target Information
The TYR-related proteins TRP1 and TRP2 are specifically expressed in melanocytes and contribute to melanin synthesis within melanosomes. These TRPs, including TYR, share a similar transmembrane region, contain two metal-binding regions and a cysteine-rich epidermal growth factor motif, and are localized in the melanosomal membrane. Although they share structural similarities, they have distinct catalytic activities and individually contribute to melanin biopolymer biosynthesis. TRPs are believed to form a multi-enzyme complex, where TRP1 expression helps stabilize TYR in melanocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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