Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody
BAIAP2L1 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 면역형광 분석에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BAIAP2L1 (Accession Q9UHR4), corresponding to amino acid residues K113–Y163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899528 |
Product Specific Information
Antibody detects endogenous levels of total BAIAP2L1.
Target Information
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided into two groups, IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain.
The protein encoded by this gene contains a conserved IMD (F-actin bundling domain) at the N-terminus and a canonical SH3 domain near the C-terminus, classifying it as IRSp53-like.
It acts as a substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. The protein is involved in signal transduction pathways that link plasma membrane deformation and actin cytoskeleton remodeling.
Overexpression promotes actin assembly and membrane protrusions in mammalian cells, and it is essential for forming a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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