
ELK Biotechnology NUDT5 rabbit pAb
NUDT5 단백질을 인식하는 토끼 폴리클로날 항체로, WB에 사용 가능. 사람, 마우스, 랫트에 반응하며 핵 내 단백질 검출에 적합. 합성 펩타이드 면역원 사용, 고순도 IgG 형태로 제공. -20°C에서 1년 보관 가능.
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NUDT5 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NUDT5 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human NUDT5 (AA range: 95–145) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 11164 |
| Human Swiss-Prot No. | Q9UKK9 |
| Cellular localization | Nucleus |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
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