ELK Biotechnology NYX rabbit pAb
NYX 단백질에 특이적인 토끼 다클론 항체로, Western Blot에 최적화됨. 인간 및 생쥐 시료에 반응하며, 고순도의 IgG 형태로 제공. -20°C에서 1년 보관 가능하며, 시각 관련 연구에 적합.
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ELK Biotechnology NYX rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NYX rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human NYX (AA 139–189) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 60506 |
| Human Swiss-Prot No. | Q9GZU5 |
| Cellular localization | Secreted, extracellular space, extracellular matrix |
| Species Reactivity | Human, Mouse |
Background
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus, and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. (provided by RefSeq, Oct 2008)
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