ELK Biotechnology PCDB7 rabbit pAb

제품명

PCDB7 rabbit pAb

제품 설명

PCDB7 단백질을 인식하는 토끼 폴리클로날 항체입니다. 인간, 생쥐, 랫트 시료에서 사용 가능하며, Western blot, ELISA, 면역조직화학(IHC) 등 다양한 응용에 적합합니다.

제품 정보

Background

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3′ exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site. (provided by RefSeq, Jul 2008)