ELK Biotechnology PCDBB rabbit pAb

제품명

PCDBB rabbit pAb

공급업체

ELK Biotechnology

제품 설명

PCDBB rabbit pAb는 인간 PCDBB 단백질에서 유래한 합성 펩타이드를 면역원으로 제작된 토끼 폴리클로날 항체입니다. WB 및 IHC 분석에 사용되며, 세포막 단백질 검출에 적합합니다.

제품 스펙

Background

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.
The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily.
The extracellular domains interact in a homophilic manner to specify differential cell-cell connections.
Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected.
These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
[provided by RefSeq, Jul 2008]